Anything foreign to the body on a regular daily basis is not good, regardless of what it is. I do know first hand that aspartame can and does cause havoc in other ways. For my friend headaches, for me extreme joint pain especially if on Liptor . We figured this out years ago by process of elimination. I stopped all artificial sweeteners years back. Did use pure Stevia for awhile. Back on sugar for coffee and tea, Too much of anything can be bad for us.
Different people are sensitive to different things, be they foods, drugs, or other chemicals. Some people may be affected by statins adversely and others by aspartame. Garlic, onions, and wheat affect others.